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CD45RB 抗体

CD45RB 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-55 unconjugated
产品编号 ABIN2664724
发货至: 中国
  • 抗原 See all CD45RB 抗体
    CD45RB
    适用
    • 57
    • 18
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    • 5
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    • 2
    宿主
    • 47
    • 18
    • 12
    小鼠
    克隆类型
    • 76
    • 1
    单克隆
    标记
    • 23
    • 8
    • 8
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    • 5
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    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
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    This CD45RB antibody is un-conjugated
    应用范围
    • 74
    • 41
    • 35
    • 26
    • 21
    • 17
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    • 4
    • 1
    • 1
    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    MEM-55
    亚型
    IgG2b kappa
    Top Product
    Discover our top product CD45RB Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD45RB
    别名
    CD45RB (CD45RB 产品)
    背景
    CD45RB is a 180-240 kD single chain type I membrane glycoprotein. It is an exon 5 splice variant of the tyrosine phosphatase CD45. The CD45RB isoform is expressed on thymocytes, T cell subsets, B cells, monocytes/macrophages, granulocytes, and dendritic cells. CD45RB enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines. The MEM-55 antibody recognizes a silaidase-sensitive epitope of CD45.
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