CD41, CD61 抗体
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北京 101111
Quick Overview for CD41, CD61 抗体 (ABIN2664684)
抗原
See all CD41, CD61 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- The antibody was purified by affinity chromatography.
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亚型
- IgM kappa
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anti-CD41,CD61 antibody
适用: 人, Cow FACS, IP, ELISA, ICC 宿主: 小鼠 Monoclonal IVA30 unconjugated
anti-CD41,CD61 (PAC-1 epitope) antibody适用: 人 FACS, IP, ICC 宿主: 小鼠 Monoclonal PAC-1 unconjugated
anti-CD41,CD61 antibody适用: Cow, 绵羊, Cat, 犬, 山羊, 马, 兔 FACS, IP, ELISA 宿主: 小鼠 Monoclonal CO-35E4 unconjugated
anti-CD41,CD61 antibody (PE)适用: 小鸡 FACS 宿主: 小鼠 Monoclonal 11C3 PE
anti-CD41,CD61 (PAC-1 epitope) antibody (PE)适用: 人 FACS 宿主: 小鼠 Monoclonal PAC-1 PE
anti-CD41,CD61 (PAC-1 epitope) antibody (PerCP)适用: 人 FACS 宿主: 小鼠 Monoclonal PAC-1 PerCP
anti-CD41,CD61 (PAC-1 epitope) antibody (FITC)适用: 人 FACS 宿主: 小鼠 Monoclonal PAC-1 FITC
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- CD41, CD61 (CD41,CD61)
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别名
- CD41/CD61
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背景
- The gpIIb/IIIa complex, also known as integrin αIIbβ3, is expressed by megakaryocytes and platelets. It undergoes conformational changes upon activation by substances, such as ADP, thrombin, and TXA2, which subsequently reveals a ligand binding site that is specific for fibrinogen, von Willebrand factor (vWF), fibronectin, and vitronectin. This conformational change is crucial for platelet-platelet adhesion. Ligand bound gpIIb/IIIa complex promotes platelet aggregation. This complex plays an important role in hemostasis and is a target for developing therapeutic antibodies in immune thrombocytopenia.
抗原
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