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- 抗原 See all CD41, CD61 抗体
- CD41, CD61 (CD41,CD61)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD41, CD61 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- The antibody was purified by affinity chromatography.
- 克隆位点
- PAC-1
- 亚型
- IgM kappa
- Top Product
- Discover our top product CD41, CD61 Primary Antibody
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anti-CD41,CD61 antibody
适用: 人, Cow FACS, IP, ELISA, ICC 宿主: 小鼠 Monoclonal IVA30 unconjugated
anti-CD41,CD61 antibody适用: 人 FACS, IP, ICC 宿主: 小鼠 Monoclonal PAC-1 unconjugated
anti-CD41,CD61 antibody适用: Cow, 绵羊, Cat, 犬, 山羊, 马, 兔 FACS, IP, ELISA 宿主: 小鼠 Monoclonal CO-35E4 unconjugated
anti-CD41,CD61 antibody (PE)适用: 小鸡 FACS 宿主: 小鼠 Monoclonal 11C3 PE
anti-CD41,CD61 antibody (PerCP)适用: 人 FACS 宿主: 小鼠 Monoclonal PAC-1 PerCP
anti-CD41,CD61 antibody (PE)适用: 人 FACS 宿主: 小鼠 Monoclonal PAC-1 PE
anti-CD41,CD61 antibody (FITC)适用: 人 FACS 宿主: 小鼠 Monoclonal PAC-1 FITC
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- CD41, CD61 (CD41,CD61)
- 别名
- CD41/CD61 (CD41, CD61 产品)
- 背景
- The gpIIb/IIIa complex, also known as integrin αIIbβ3, is expressed by megakaryocytes and platelets. It undergoes conformational changes upon activation by substances, such as ADP, thrombin, and TXA2, which subsequently reveals a ligand binding site that is specific for fibrinogen, von Willebrand factor (vWF), fibronectin, and vitronectin. This conformational change is crucial for platelet-platelet adhesion. Ligand bound gpIIb/IIIa complex promotes platelet aggregation. This complex plays an important role in hemostasis and is a target for developing therapeutic antibodies in immune thrombocytopenia.
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