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PDCD1LG2 抗体

PDCD1LG2 适用: 人 FACS, IHC, IF 宿主: 小鼠 Monoclonal MIH18 unconjugated
产品编号 ABIN2664474
发货至: 中国
  • 抗原 See all PDCD1LG2 抗体
    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This PDCD1LG2 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    MIH18
    亚型
    IgG1 kappa
    Top Product
    Discover our top product PDCD1LG2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
    别名
    CD273 (PDCD1LG2 产品)
    背景
    CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions. Clone MIH18 is reported to block PDL2.
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