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CD22 抗体

This anti-CD22 antibody is a 小鼠 单克隆 antibody detecting CD22 in FACS, CyTOF 和 DNA Mic. Suitable for 人.
产品编号 ABIN2664405
发货至: 中国

Quick Overview for CD22 抗体 (ABIN2664405)

抗原

See all CD22 抗体
CD22 (CD22 Molecule (CD22))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD22 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF), DNA Microscopy (DNA Mic)

克隆位点

S-HCL-1
  • 纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG2b kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CD22 (CD22 Molecule (CD22))

    别名

    CD22

    背景

    CD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM and is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial.
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