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PROCR 抗体

This anti-PROCR antibody is a 大鼠 单克隆 antibody detecting PROCR in ICFC. Suitable for 人.
产品编号 ABIN2664373
发货至: 中国

Quick Overview for PROCR 抗体 (ABIN2664373)

抗原

See all PROCR 抗体
PROCR (Protein C Receptor, Endothelial (PROCR))

适用

  • 56
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宿主

  • 58
  • 13
  • 8
大鼠

克隆类型

  • 59
  • 20
单克隆

标记

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This PROCR antibody is un-conjugated

应用范围

  • 60
  • 41
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Intracellular Flow Cytometry (ICFC)

克隆位点

RCR-401
  • 纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    PROCR (Protein C Receptor, Endothelial (PROCR))

    别名

    CD201

    背景

    Endothelial protein C receptor (EPCR), also known as CD201, is a 46 kD N-glycosylated type I transmembrane protein primarily expressed on the endothelial cells of arteries and veins in heart and lung. It is also expressed at high levels on a subset of hematopoietic stem cells and a subset of dendritic cells. CD201 functions as a primary receptor for protein C activation, which results in inhibition of both intrinsic and extrinsic coagulation pathways. It also plays an important role in many pathophysiologic processes, such as inflammation responses to infection, trauma, hematopoiesis, and autoimmune response. Deletion of the CD201 gene in knock-out mice leads to embryonic lethality before embryonic day 10, indicating that CD201 expression is critical for embryo development. In humans, mutations of CD201 have been associated with venous thromboembolism and myocardial infarction as well as with late fetal loss during pregnancy.
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