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CXCR4 抗体

This anti-CXCR4 antibody is a 小鼠 单克隆 antibody detecting CXCR4 in BCA. Suitable for 人.
产品编号 ABIN2664313
发货至: 中国

Quick Overview for CXCR4 抗体 (ABIN2664313)

抗原

See all CXCR4 抗体
CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CXCR4 antibody is un-conjugated

应用范围

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Biochemical Assay (BCA)

克隆位点

12G5
  • 交叉反应

    Chimpanzee, Baboon, Cynomolgus, 猕猴, Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops), Sooty mangabey (Cercocebus atys), Green Monkey (Chlorocebus sabaeus)

    纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and EDTA.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

    别名

    CD184

    背景

    CD184, also known as fusin or CXCR4, is a 45 kD seven transmembrane G-protein-linked CXC chemokine receptor. CD184 is widely expressed on blood and tissue cells, including B and T cells, monocytes, macrophages, dendritic cells, granulocytes, megakaryocytes/platelets, lymphoid, myeloid precursor cells, endothelial cells, epithelial cells, astrocytes, and neurons, among other tissue cells. CD184 is the receptor for CXC chemokine SDF-1, mediates blood cell migration, and is involved in B lymphopoiesis and myelopoiesis, cardiogenesis, blood vessel formation, and cerebellar development. CXCR4 is also a coreceptor of X4 HIV-1 and an alternative receptor for some isolates of HIV-2.

    途径

    Regulation of Cell Size, CXCR4-mediated Signaling Events
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