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CD180 抗体

CD180 适用: 人 FACS 宿主: 小鼠 Monoclonal MHR73-11 unconjugated
产品编号 ABIN2664307
发货至: 中国
  • 抗原 See all CD180 抗体
    CD180 (CD180 Molecule (CD180))
    适用
    • 19
    • 9
    • 2
    • 1
    宿主
    • 11
    • 8
    • 3
    小鼠
    克隆类型
    • 11
    • 11
    单克隆
    标记
    • 16
    • 3
    • 2
    • 1
    This CD180 antibody is un-conjugated
    应用范围
    • 12
    • 11
    • 7
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    Flow Cytometry (FACS)
    交叉反应
    Baboon, Cynomolgus, 猕猴
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    MHR73-11
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD180 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD180 (CD180 Molecule (CD180))
    别名
    CD180 (CD180 产品)
    背景
    CD180, also known as RP105, is a 105 kD member of the toll-like receptor (TLR) family and is expressed on most B cells, monocytes/macrophages and dendritic cells. The TLR family's structural characteristics are critically involved in protein-protein signaling interactions leading to the activation of the innate immune system. Additionally, MD-1, a secretory protein, associates with CD180 (RP105) at the cell surface and this complex, in conjunction with TLR4, recognizes bacterial LPS. The human CD180 (RP105) gene maps to 5q12. The MHR73-11 antibody is able to activate B cells and to protect against irradiation- or dexamethasone-induced apoptosis.
    途径
    Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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