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SIRPB1 抗体

SIRPB1 适用: 人 IHC, IF, FACS 宿主: 小鼠 Monoclonal B4B6 unconjugated
产品编号 ABIN2664295
发货至: 中国
  • 抗原 See all SIRPB1 抗体
    SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))
    适用
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    宿主
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    小鼠
    克隆类型
    • 32
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    单克隆
    标记
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    This SIRPB1 antibody is un-conjugated
    应用范围
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    Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
    产品特性
    The B4B6 antibody recognizes human CD172b also known as signal-regulatory protein beta, and SIRP-beta. CD172b is a member of the signal regulatory protein family and immunoglobulin superfamily. CD172b contains a single pass transmembrane region with immunoglobulin-like domains and unlike CD172a, this receptor lacks a cytoplasmic SHP-2 binding domain. CD172b is a disulfide-linked homodimer with a predicted molecular weight of approximately 43 kD. Two isoforms of CD172b are produced by alternative splicing. CD172b is expressed on myeloid cells including monocytes and dendritic cells where it functions in the negative regulation of tyrosine-kinase coupled signaling processes. CD172b has been shown to regulate neutrophil transepithelial migration. CD172b interacts with DAP12 and Syk kinase (through TYROBP). The B4B6 antibody has been shown to be useful for flow cytometry.
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    B4B6
    亚型
    IgG1 kappa
    Top Product
    Discover our top product SIRPB1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))
    别名
    CD172b (SIRPB1 产品)
    别名
    CD172b antibody, SIRP-BETA-1 antibody, SIRPB1 antibody, SIRPG antibody, signal regulatory protein beta 1 antibody, signal-regulatory protein beta-1 antibody, signal-regulatory protein beta-1 isoform 3 antibody, SIRPB1 antibody, LOC458036 antibody, LOC458430 antibody, LOC485809 antibody, LOC715912 antibody, LOC100458151 antibody
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