SIRPB1 抗体
Quick Overview for SIRPB1 抗体 (ABIN2664295)
抗原
See all SIRPB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- The B4B6 antibody recognizes human CD172b also known as signal-regulatory protein beta, and SIRP-beta. CD172b is a member of the signal regulatory protein family and immunoglobulin superfamily. CD172b contains a single pass transmembrane region with immunoglobulin-like domains and unlike CD172a, this receptor lacks a cytoplasmic SHP-2 binding domain. CD172b is a disulfide-linked homodimer with a predicted molecular weight of approximately 43 kD. Two isoforms of CD172b are produced by alternative splicing. CD172b is expressed on myeloid cells including monocytes and dendritic cells where it functions in the negative regulation of tyrosine-kinase coupled signaling processes. CD172b has been shown to regulate neutrophil transepithelial migration. CD172b interacts with DAP12 and Syk kinase (through TYROBP). The B4B6 antibody has been shown to be useful for flow cytometry.
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纯化方法
- The antibody was purified by affinity chromatography.
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亚型
- IgG1 kappa
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anti-Signal-Regulatory Protein beta 1 (SIRPB1) (AA 30-371) antibody
SIRPB1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein beta 1 (SIRPB1) (AA 30-206), (Isoform 3) antibodySIRPB1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein beta 1 (SIRPB1) antibodySIRPB1 适用: 人, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein beta 1 (SIRPB1) (AA 127-356) antibodySIRPB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein beta 1 (SIRPB1) (AA 17-43), (N-Term) antibodySIRPB1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB45115 unconjugated
anti-Signal-Regulatory Protein beta 1 (SIRPB1) antibodySIRPB1 适用: 人 FACS 宿主: 小鼠 Monoclonal B4B6 unconjugated
anti-Signal-Regulatory Protein beta 1 (SIRPB1) antibody (PE)SIRPB1 适用: 人 FACS 宿主: 小鼠 Monoclonal B4B6 PE
anti-Signal-Regulatory Protein beta 1 (SIRPB1) (AA 129-342) antibodySIRPB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))
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别名
- CD172b
抗原
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