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SIRPA 抗体

This anti-SIRPA antibody is a 小鼠 单克隆 antibody detecting SIRPA in FACS, IHC 和 IF. Suitable for 大鼠.
产品编号 ABIN2664292
发货至: 中国

Quick Overview for SIRPA 抗体 (ABIN2664292)

抗原

See all SIRPA 抗体
SIRPA (Signal-Regulatory Protein alpha (SIRPA))

适用

  • 83
  • 41
  • 36
  • 10
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  • 3
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  • 3
大鼠

宿主

  • 68
  • 39
  • 1
  • 1
  • 1
小鼠

克隆类型

  • 61
  • 48
  • 1
单克隆

标记

  • 66
  • 10
  • 5
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This SIRPA antibody is un-conjugated

应用范围

  • 69
  • 53
  • 28
  • 25
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  • 17
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  • 10
  • 3
  • 1
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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

克隆位点

OX-41
  • 纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    SIRPA (Signal-Regulatory Protein alpha (SIRPA))

    别名

    CD172a

    背景

    Rat CD172a, also known as a signal-regulatory protein α (SIRPα), is a 75-110 kD transmembrane glycoprotein involved in the receptor tyrosine kinase coupled signaling pathway. It belongs to the Ig superfamily primarily expressed on monocytes/macrophages, granulocytes, dendritic cells and neurons. CD172a serves as a substrate of activated receptor ttyrosine kinases (RTKs). The interaction of the CD172a intracellular domain with SHP-1 and SHP-2 displays negative signaling in the regulation of leukocyte adhesion and transmigration, T cell activation, macrophage fusion and phagocytosis. CD47 (IAP) is an extracellular ligand for CD172a.
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