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IFNGR1 抗体

IFNGR1 适用: 小鼠 IHC, FACS, IF 宿主: 仓鼠 Monoclonal 2E2 unconjugated
产品编号 ABIN2664150
发货至: 中国
  • 抗原 See all IFNGR1 抗体
    IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))
    适用
    • 55
    • 27
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    小鼠
    宿主
    • 51
    • 9
    • 7
    • 5
    • 1
    仓鼠
    克隆类型
    • 55
    • 17
    • 1
    单克隆
    标记
    • 46
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    • 3
    • 1
    • 1
    • 1
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    This IFNGR1 antibody is un-conjugated
    应用范围
    • 49
    • 28
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    • 20
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    • 8
    • 6
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    Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    2E2
    亚型
    IgG
    Top Product
    Discover our top product IFNGR1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))
    别名
    CD119 (IFNGR1 产品)
    背景
    CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.
    途径
    Interferon-gamma Pathway
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