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CCL17 抗体

This 山羊 多克隆 anti-CCL17 antibody (Clone Poly5230) specifically detects CCL17 in IHC, IP 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN2664095
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CCL17 抗体 (ABIN2664095)

抗原

See all CCL17 抗体
CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

适用

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宿主

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山羊

克隆类型

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多克隆

标记

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This CCL17 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS)

克隆位点

Poly5230
  • 纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))

    别名

    CCL17

    背景

    CCL17 was initially isolated from phytohemagglutinin-stimulated PBMCs. CCL17 is constitutively expressed in the thymus and, under activation, in several cell types. CCL17-mediated recruitment of Th2 cells and CLA+ CD4+ T cells plays a key role in allergic diseases like atopic dermatitis, allergic asthma, allergic rhinitis, and allergic contact dermatitis. In addition, CCL17 has been detected in idiopathic pulmonary fibrosis. Also, CCL17 and CCL22 secreted by dendritic cells seem to mediate the recruitment of regulatory T cells to sites of inflammation in patients with chronic hepatitis. CCL17 is upregulated by several combinations of cytokines: TNF-α, IL-4, and IFN-γ in bronchial epithelial cells, TGF-β1, TNF-α, and IFN-γ in human keratinocyte cell lines, and histamine and prostaglandin E2P in immature dendritic cells.
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