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BCL6 抗体

BCL6 适用: 人, 小鼠 FACS 宿主: 小鼠 Monoclonal IG191E-A8 unconjugated
产品编号 ABIN2664064
发货至: 中国
  • 抗原 See all BCL6 抗体
    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
    适用
    • 119
    • 57
    • 26
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 71
    • 48
    • 1
    小鼠
    克隆类型
    • 60
    • 60
    单克隆
    标记
    • 70
    • 10
    • 4
    • 3
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    • 3
    • 3
    • 3
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    • 3
    This BCL6 antibody is un-conjugated
    应用范围
    • 66
    • 38
    • 35
    • 33
    • 32
    • 15
    • 13
    • 11
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    IG191E-A8
    亚型
    IgG1
    Top Product
    Discover our top product BCL6 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
    别名
    Bcl-6 (BCL6 产品)
    背景
    B-cell lymphoma 6 (Bcl-6), is an 80 kD homodimer and member of the BTB-POZ zinc finger family. It consists of one BTB (POZ) domain and six C2H2-type zinc fingers. Bcl-6 is a transcriptional repressor as well as a master regulator of germinal center reaction. On B cells, Bcl-6 induces proliferation, antibody class switching and affinity maturation, while inhibits its differentiation to plasma cells. On T cells, Bcl-6 induces its differentiation to TFH. This molecule is also expressed in some B cell lymphomas and breast cancer cells.
    途径
    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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