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- 抗原 See all TREML2 抗体
- TREML2 (Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This TREML2 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
- 克隆位点
- MIH47
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product TREML2 Primary Antibody
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anti-Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (AA 188-237) antibody
TREML2 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (AA 19-268) antibodyTREML2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (AA 101-150) antibodyTREML2 适用: 人, 犬, Pig, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (N-Term) antibodyTREML2 适用: 人, 犬, Pig, 兔, Cow, 马, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.2 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- TREML2 (Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2))
- 别名
- TLT-2 (TREML2 产品)
- 别名
- TREM-B2V1 antibody, C6orf76 antibody, TLT-2 antibody, TLT2 antibody, dJ238O23.1 antibody, AW049306 antibody, Gm750 antibody, Tlt2 antibody, triggering receptor expressed on myeloid cells like 2 antibody, triggering receptor expressed on myeloid cells-like 2 antibody, TREML2 antibody, Treml2 antibody
- 背景
- Triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2, TREML2) is a type I transmembrane protein in TREM family. It consists of a single extracellular Ig-like domain of the V-type, a transmembrane domain, and a short cytoplasmic domain. TLT-2 is expressed on myeloid , B cells , and macrophages. It was also found to express on CD8+ T cells and activated CD4+ T cells. It regulates innate immune response based on its expression profile, costimulates the activation of T cells. Transduction of TLT-2 into T cells resulted in enhanced IL-2 and IFN-gamma production. It was reported that B3-H7 is a receptor of TLT-2. Blockade of the B7-H3/ TLT-2 pathway with monoclonal antibodies against B7-H3 or TLT-2 efficiently inhibited hypersensitivity response. Further studies are needed to confirm the ligand.
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