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TCR V Beta13.2 抗体 (PE)

The 小鼠 单克隆 anti-TCR V Beta13.2 antibody is suitable to detect TCR V Beta13.2 in samples from 人. It has been validated for WB.
产品编号 ABIN2663914
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TCR V Beta13.2 抗体 (PE) (ABIN2663914)

抗原

TCR V Beta13.2

适用

人

宿主

小鼠

克隆类型

单克隆

标记

PE

应用范围

Western Blotting (WB)

克隆位点

H132
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    TCR V Beta13.2

    背景

    The Vβ13.2 TCR is a variant of the TCR β chain. It belongs to Ig superfamily and is expressed by a subset of peripheral blood T cells and some T cell clones. Vβ expression in humans and mice has been used to study the effects of superantigens and also to examine the repertoires of T cells involved in inflammatory and autoimmune disease. It is reported that Vβ13.2 TCRs possess very unusually long β-chain CDR3 regions and are expressed on CTL specific for the immunodominant human HLA-B8-restricted HIV-1 nef epitope, FLKEKGGL (FL8). CTL expressing V β13.2 TCRs tolerate naturally arising viral variants in the FL8 epitope that escape recognition by other CTL. The clone H132 recognizes the Vβ13.2 allele product but does not react with the Vβ13.1, 13.3, 13.5 and 13.6 allele products of the Vβ13 subfamily.
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