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Selectin E/CD62e 抗体 (PE)

This anti-Selectin E/CD62e antibody is a 小鼠 单克隆 antibody detecting Selectin E/CD62e in WB 和 IF. Suitable for 人.
产品编号 ABIN2663545
发货至: 中国

Quick Overview for Selectin E/CD62e 抗体 (PE) (ABIN2663545)

抗原

See all Selectin E/CD62e (SELE) 抗体
Selectin E/CD62e (SELE) (Selectin E (SELE))

适用

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宿主

  • 73
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小鼠

克隆类型

  • 80
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单克隆

标记

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This Selectin E/CD62e antibody is conjugated to PE

应用范围

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Western Blotting (WB), Immunofluorescence (IF)

克隆位点

HAE-1f
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    Selectin E/CD62e (SELE) (Selectin E (SELE))

    别名

    CD62E

    背景

    CD62E (also known as E-selectin, ELAM-1, and LECAM-1) is a 115 kD type I membrane protein and a member of the selectin family. CD62E is highly expressed on activated endothelial cells (IL-2, TNF-α, other cytokines can increase expression) and can also be expressed on endothelial cells in the skin, bone marrow and placenta. CD62E is involved in tethering and leucocyte rolling on activated endothelium at inflammatory sites and may also play a role in tumor metastasis and angiogenesis. CD62E binds to both Siayl Lewis X (CD15s) and PSGL-1 (CD162).The HAE-1f antibody has been shown to recognize human CD62E and to be useful for flow cytometry and in vitro blocking.

    途径

    Thromboxane A2 Receptor Signaling
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