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- 抗原 See all CD51/CD61 (ITGAV/ITGB3) 抗体
- CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD51/CD61 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 交叉反应
- 兔, 小鸡
- 纯化方法
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
- 克隆位点
- 23C6
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product ITGAV/ITGB3 Primary Antibody
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anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibody
ITGAV/ITGB3 适用: 人, 小鼠, 大鼠 FACS, WB, IHC (fro), IF (cc), IF (p), ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibodyITGAV/ITGB3 适用: 人, 小鸡, 兔 FACS, IHC (fro), IHC 宿主: 小鼠 Monoclonal 23C6 unconjugated
anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibody (FITC)ITGAV/ITGB3 适用: 人 FACS 宿主: 小鼠 Monoclonal 23C6 FITC
anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibodyITGAV/ITGB3 适用: 人, 小鸡 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal 23C6 unconjugated
anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibody (PE)ITGAV/ITGB3 适用: 人, 小鸡 FACS 宿主: 小鼠 Monoclonal 23C6 PE
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
- 别名
- CD51/61 (ITGAV/ITGB3 产品)
- 背景
- CD51/CD61 is an integrin complex known as αVβ3. It is expressed at high levels on osteoclasts, endothelial cells, and melanoma cells and at low levels on platelets and macrophages. CD51 is a heterodimer composed of disulfide-linked 125 kD and 24 kD proteins. CD61 is also a member of the integrin family known as gpIIIa or β3 integrin. It is a 110 kD common β subunit of CD51/CD61 or CD41/CD61 complex. CD51/CD61, also known as the vitronectin receptor, mediates the binding of platelets to immobilized vitronectin without prior activation. Other ligands include RGD-containing proteins such as fibrinogen, fibronectin, von Willebrand factor (vWf), laminin, thrombospondin and the neural adhesion molecule L1. CD51/CD61 also mediates cell-cell adhesion via interaction with CD31. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins, including matrix components. The 23C6 antibody has been reported to be useful for blocking studies.
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