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ITGA2 抗体 (PE)

This PE-conjugated 仓鼠 单克隆 anti-ITGA2 antibody (Clone HMalpha2) specifically detects ITGA2 in FACS 和 CyTOF. The antibody is reactive with 小鼠 samples.
产品编号 ABIN2663499
发货至: 中国
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Quick Overview for ITGA2 抗体 (PE) (ABIN2663499)

抗原

See all ITGA2 抗体
ITGA2 (Integrin alpha 2 (ITGA2))

适用

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小鼠

宿主

  • 82
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仓鼠

克隆类型

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单克隆

标记

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This ITGA2 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)

克隆位点

HMalpha2
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    ITGA2 (Integrin alpha 2 (ITGA2))

    别名

    CD49b

    背景

    CD49b is a 150 kD glycoprotein, also known as α2 integrin, VLA-2 α chain, Integrin α2 chain, and HMα2. It is a member of the integrin family, expressed on NK cells, a subset of splenic CD4+ T cells, NK-T cells, intestinal intraepithelial and lamina propria lymphocytes, epithelial cells, and platelets. By associating with CD29 (integrin β1 subunit), CD49b forms the VLA-2 (integrin α2β1 ) complex. It plays a critical role in both adhesion and lymphocyte activation. The primary ligands for CD49b are collagen, laminin, and fibronectin. The HMα2 antibody has been shown to be useful for partially blocking CD49b mediated interactions with collagen. Additionally, this antibody blocks staining of splenic NK cells by the monoclonal antibody DX5.

    途径

    CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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