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CD45RB 抗体 (PE)

This anti-CD45RB antibody is a 小鼠 单克隆 antibody detecting CD45RB in FACS. Suitable for 人.
产品编号 ABIN2663485
发货至: 中国

Quick Overview for CD45RB 抗体 (PE) (ABIN2663485)

抗原

See all CD45RB 抗体
CD45RB

适用

  • 93
  • 18
  • 10
  • 6
  • 5
  • 4
  • 3
  • 2

宿主

  • 62
  • 33
  • 18
小鼠

克隆类型

  • 102
  • 10
  • 1
单克隆

标记

  • 29
  • 11
  • 9
  • 8
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 6
  • 5
  • 1
  • 1
  • 1
This CD45RB antibody is conjugated to PE

应用范围

  • 87
  • 77
  • 61
  • 46
  • 36
  • 21
  • 17
  • 7
  • 4
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

MEM-55
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

    亚型

    IgG2b kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CD45RB

    别名

    CD45RB

    背景

    CD45RB is a 180-240 kD single chain type I membrane glycoprotein. It is an exon 5 splice variant of the tyrosine phosphatase CD45. The CD45RB isoform is expressed on thymocytes, T cell subsets, B cells, monocytes/macrophages, granulocytes, and dendritic cells. CD45RB enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines. The MEM-55 antibody recognizes a silaidase-sensitive epitope of CD45.
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