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CD45RB 抗体 (PE)

This anti-CD45RB antibody is a 大鼠 单克隆 antibody detecting CD45RB in FACS, IHC 和 IF. Suitable for 小鼠.
产品编号 ABIN2663484
发货至: 中国

Quick Overview for CD45RB 抗体 (PE) (ABIN2663484)

抗原

See all CD45RB 抗体
CD45RB

适用

  • 93
  • 18
  • 10
  • 6
  • 5
  • 4
  • 3
  • 2
小鼠

宿主

  • 62
  • 33
  • 18
大鼠

克隆类型

  • 102
  • 10
  • 1
单克隆

标记

  • 29
  • 11
  • 9
  • 8
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 6
  • 5
  • 1
  • 1
  • 1
This CD45RB antibody is conjugated to PE

应用范围

  • 87
  • 77
  • 61
  • 46
  • 36
  • 21
  • 17
  • 7
  • 4
  • 1
  • 1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

克隆位点

C363-16A
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CD45RB

    别名

    CD45RB

    背景

    CD45RB is an isoform of CD45 with exon 5 splicing (encodes B determinant). It is a 220 kD glycoprotein expressed on peripheral B cells, naive T cells, thymocytes, weakly on macrophages, and dendritic cells. It plays a critical role in TCR and BCR signaling. As T cells become activated and progress from naive to memory cells, CD45RB expression is downregulated. Additionally, functionally distinct CD4+ T cell subsets, which secrete differing cytokine profiles, can be separated by CD45RB intensity. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4 and Thy-1.
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