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CD200 抗体 (PE)

This anti-CD200 antibody is a 小鼠 单克隆 antibody detecting CD200 in FACS, ELISA, IP 和 BR. Suitable for 大鼠.
产品编号 ABIN2663154
发货至: 中国

Quick Overview for CD200 抗体 (PE) (ABIN2663154)

抗原

See all CD200 抗体
CD200

适用

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大鼠

宿主

  • 71
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  • 18
  • 1
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小鼠

克隆类型

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  • 3
单克隆

标记

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This CD200 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP), Blocking Reagent (BR)

克隆位点

OX-2
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CD200

    别名

    CD200

    背景

    CD200, known as OX-2, is a type I membrane glycoprotein member of the Ig supergene family. CD200 is expressed on B cells, a subset of T cells, thymocytes, follicular dendritic cells, neurons, keratinocytes, vascular endothelium, and some smooth muscle. The interaction of CD200 with CD200 receptor provide a potent costimulatory T-cell signal in the presence of TCR signaling, stimulate macrophages, and inhibit mast cell degranulation. It was reported that increased expression of OX-2 on DC was associated with inhibition of cytokine production and renal allograft rejection. Incubation of lymphocytes with OX-2 Fc inhibits a primary mixed lymphocyte reaction in vitro, decreased IL-2 and IFN-γ production, increased IL-4 and IL-10 production. In vivo infusion of OX-2 Fc promotes both skin and renal graft survival and decreases the antibody response. The OX-2 antibody reacts with rat OX-2 antigen.
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