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CD180 抗体 (PE)

CD180 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal RP-14 PE
产品编号 ABIN2663108
发货至: 中国
  • 抗原 See all CD180 抗体
    CD180 (CD180 Molecule (CD180))
    适用
    • 18
    • 9
    • 3
    • 1
    小鼠
    宿主
    • 12
    • 6
    • 2
    大鼠
    克隆类型
    • 12
    • 8
    单克隆
    标记
    • 16
    • 2
    • 1
    • 1
    This CD180 antibody is conjugated to PE
    应用范围
    • 12
    • 9
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    RP-14
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CD180 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD180 (CD180 Molecule (CD180))
    别名
    CD180 (CD180 产品)
    别名
    Ly78 antibody, CD180 antibody, LY64 antibody, RP105 antibody, F630107B15 antibody, CD180 molecule antibody, CD180 antigen antibody, Cd180 antibody, CD180 antibody
    背景
    CD180 is a 105 kD type I membrane protein, also known as RP105 or Ly64. It is a member of the toll-like receptor family consisting of an extracellular leucine-rich repeat (LRR) and a short cytoplasmic tail. It is expressed on most B cells, monocytes/macrophages, and dendritic cells. CD180 associates with MD-1 to form the RP105/MD-1 surface receptor. CD180/MD-1, by working in concert with TLR4, controls B cell recognition and signalling of bacterial LPS. The ligation of RP105 by RP/14 leads to a strong B cell proliferative response, as well as protection from apoptosis induced by radiation or dexamethasone. Interestingly, in some systems, ligation of RP105 leads to Fas-independent apoptosis.
    途径
    Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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