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CD180 抗体 (PE)

This anti-CD180 antibody is a 大鼠 单克隆 antibody detecting CD180 in FACS. Suitable for 小鼠.
产品编号 ABIN2663108
发货至: 中国

Quick Overview for CD180 抗体 (PE) (ABIN2663108)

抗原

See all CD180 抗体
CD180 (CD180 Molecule (CD180))

适用

  • 23
  • 9
  • 2
  • 1
小鼠

宿主

  • 12
  • 11
  • 3
大鼠

克隆类型

  • 14
  • 12
单克隆

标记

  • 20
  • 3
  • 2
  • 1
This CD180 antibody is conjugated to PE

应用范围

  • 14
  • 13
  • 8
  • 7
  • 7
  • 5
  • 5
  • 4
  • 3
  • 2
Flow Cytometry (FACS)

克隆位点

RP-14
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CD180 (CD180 Molecule (CD180))

    别名

    CD180

    背景

    CD180 is a 105 kD type I membrane protein, also known as RP105 or Ly64. It is a member of the toll-like receptor family consisting of an extracellular leucine-rich repeat (LRR) and a short cytoplasmic tail. It is expressed on most B cells, monocytes/macrophages, and dendritic cells. CD180 associates with MD-1 to form the RP105/MD-1 surface receptor. CD180/MD-1, by working in concert with TLR4, controls B cell recognition and signalling of bacterial LPS. The ligation of RP105 by RP/14 leads to a strong B cell proliferative response, as well as protection from apoptosis induced by radiation or dexamethasone. Interestingly, in some systems, ligation of RP105 leads to Fas-independent apoptosis.

    途径

    Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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