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CD180 抗体 (PE)

CD180 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal RP-14 PE
产品编号 ABIN2663108
发货至: 中国
  • 抗原 See all CD180 抗体
    CD180 (CD180 Molecule (CD180))
    适用
    • 21
    • 9
    • 2
    • 1
    小鼠
    宿主
    • 12
    • 9
    • 3
    大鼠
    克隆类型
    • 12
    • 12
    单克隆
    标记
    • 18
    • 3
    • 2
    • 1
    This CD180 antibody is conjugated to PE
    应用范围
    • 13
    • 12
    • 8
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    RP-14
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CD180 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD180 (CD180 Molecule (CD180))
    别名
    CD180 (CD180 产品)
    背景
    CD180 is a 105 kD type I membrane protein, also known as RP105 or Ly64. It is a member of the toll-like receptor family consisting of an extracellular leucine-rich repeat (LRR) and a short cytoplasmic tail. It is expressed on most B cells, monocytes/macrophages, and dendritic cells. CD180 associates with MD-1 to form the RP105/MD-1 surface receptor. CD180/MD-1, by working in concert with TLR4, controls B cell recognition and signalling of bacterial LPS. The ligation of RP105 by RP/14 leads to a strong B cell proliferative response, as well as protection from apoptosis induced by radiation or dexamethasone. Interestingly, in some systems, ligation of RP105 leads to Fas-independent apoptosis.
    途径
    Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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