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XBP-1s 抗体 (PE)

The PE-conjugated 小鼠 单克隆 anti-XBP-1s antibody (Clone 143F) (ABIN2662901) specifically detects XBP-1s in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN2662901
发货至: 中国
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Quick Overview for XBP-1s 抗体 (PE) (ABIN2662901)

抗原

XBP-1s

适用

宿主

小鼠

克隆类型

单克隆

标记

PE

应用范围

Flow Cytometry (FACS)

克隆位点

143F
  • 纯化方法

    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    XBP-1s

    背景

    XBP-1 is a transcription factor containing a bZIP domain. It was first identified because of its ability to bind X-box, a conserved transcriptional element in the promoter of human HLA DR gene. XBP-1 has multiple functions. It controls MHC class II gene regulation and is also essential for differentiation of plasma cells. XBP-1 upregulates as part of the ER stress response, also known as the unfolded protein response. Unspliced XBP-1 is 261 amino acids and migrates on the SDS-PAGE around 33 kD, spliced XBP-1, recognized by clone 143F, is 371 amino acids and migrates around 55 kD.
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