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TREML2 抗体 (PE)

TREML2 适用: 人 FACS 宿主: 小鼠 Monoclonal MIH60 PE
产品编号 ABIN2662891
发货至: 中国
  • 抗原 See all TREML2 抗体
    TREML2 (Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This TREML2 antibody is conjugated to PE
    应用范围
    • 6
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    MIH60
    亚型
    IgG2b kappa
    Top Product
    Discover our top product TREML2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    TREML2 (Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2))
    别名
    TLT-2 (TREML2 产品)
    背景
    Trem-like transcript 2 protein (TLT2), also known as TREML2, is a 33 kD (unglycosylated) type I transmembrane protein with a single IgV domain contains two potential N-glycosylation sites, a serine/threonine-rich region with numerous predicted O-linked glycosylation sites, a single membrane-spanning region, and a short cytoplasmic tail. TLT2 is expressed on B lineage cells, macrophages, neutrophils in bone marrow and periphery, and the expression level can be upregulated in response to inflammation. As a receptor, TLT2 likely plays a role in innate immunity. Recent studies have demonstrated that ligation of TLT2 inhibits the oxidative burst in neutrophils upon fMLP stimulation, indicating that TLT2 may function as an inhibitory receptor that attenuates activation of neutrophils, and possibly macrophages. Recently TLT-2 protein has been found on CD8+ T cells and is induced on activated CD4+ T cells.
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