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- 抗原 See all TREML2 抗体
- TREML2 (Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TREML2 antibody is conjugated to PE
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应用范围
- Immunoprecipitation (IP)
- 纯化方法
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
- 克隆位点
- MIH61
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product TREML2 Primary Antibody
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anti-Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (AA 188-237) antibody
TREML2 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (AA 19-268) antibodyTREML2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (AA 101-150) antibodyTREML2 适用: 人, 犬, Pig, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2) (N-Term) antibodyTREML2 适用: 人, 犬, Pig, 兔, Cow, 马, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- TREML2 (Triggering Receptor Expressed On Myeloid Cells-Like 2 (TREML2))
- 别名
- TLT-2 (TREML2 产品)
- 别名
- TREM-B2V1 antibody, C6orf76 antibody, TLT-2 antibody, TLT2 antibody, dJ238O23.1 antibody, AW049306 antibody, Gm750 antibody, Tlt2 antibody, triggering receptor expressed on myeloid cells like 2 antibody, triggering receptor expressed on myeloid cells-like 2 antibody, TREML2 antibody, Treml2 antibody
- 背景
- Trem-like transcript 2 protein (TLT2), also known as TREML2, is a 33 kD (unglycosylated) type I transmembrane protein with a single IgV domain containing two potential N-glycosylation sites, a serine/threonine-rich region with numerous predicted O-linked glycosylation sites, a single membrane-spanning region, and a short cytoplasmic tail. TLT2 is expressed on B lineage cells, macrophages, and neutrophils in bone marrow and periphery, and the expression level can be upregulated in response to inflammation. As a receptor, TLT2 likely plays a role in innate immunity. Recent studies have demonstrated that ligation of TLT2 inhibits the oxidative burst in neutrophils upon fMLP stimulation, indicating that TLT2 may function as an inhibitory receptor that attenuates activation of neutrophils and possibly macrophages. Recently, TLT-2 protein has been found on CD8+ T cells and is induced on activated CD4+ T cells.
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