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TCR V beta 11 抗体 (PE)

适用: 小鼠 IF, IP, WB 宿主: 大鼠 Monoclonal RR3-15 PE
产品编号 ABIN2662861
发货至: 中国
  • 抗原
    TCR V beta 11
    适用
    小鼠
    宿主
    大鼠
    克隆类型
    单克隆
    标记
    PE
    应用范围
    Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    RR3-15
    亚型
    IgG2b kappa
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    TCR V beta 11
    别名
    TCR V Beta11
    背景
    T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR-β is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation. V β 11-bearing T cells are largely absent from strains of mice that express MHC class II molecule I-E. It has been demonstrated that the expression of I-E molecule is necessary for the clonal deletion of V beta 11-bearing T cells, but not sufficient for the clonal elimination of V beta 11-bearing T cells.
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