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IL-27/IL-35 EBI3 Subunit (Dimer), (Heterodimer), (Monomer) 抗体 (PE)

适用: 人 FACS 宿主: 小鼠 Monoclonal B032F6 PE
产品编号 ABIN2662763
发货至: 中国
  • 抗原
    IL-27/IL-35 EBI3 Subunit
    抗原表位
    Dimer, Heterodimer, Monomer
    适用
    宿主
    小鼠
    克隆类型
    单克隆
    标记
    PE
    应用范围
    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    B032F6
    亚型
    IgG2b kappa
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    IL-27/IL-35 EBI3 Subunit
    别名
    IL-27/IL-35 EBI3
    背景
    Epstein-Barr virus induced gene-3, also known as EBI3, is an IL-12 p40-related protein that can heterodimerize with IL-12 p35 to form IL-35, or with an IL-12 p35-related protein, p28, to form IL-27. It is produced by antigen-presenting cells such as B cells, monocytes, and dendritic cells following stimulation through TLR. It can regulate T cell differentiation and proliferation. Both IL-27 and IL-35 are anti-inflammatory cytokines that are able to inhibit Th17 generation, promote Th1 diferentiation, increase cytolytic potential of CD8+ T cells, and impact B cell differentiation and Ig production.
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