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GPR56 抗体 (PE)

This anti-GPR56 antibody is a 小鼠 单克隆 antibody detecting GPR56 in FACS 和 CyTOF. Suitable for 人.
产品编号 ABIN2662736
发货至: 中国

Quick Overview for GPR56 抗体 (PE) (ABIN2662736)

抗原

See all GPR56 抗体
GPR56 (G Protein-Coupled Receptor 56 (GPR56))

适用

  • 41
  • 20
  • 5
  • 2
  • 2

宿主

  • 35
  • 6
小鼠

克隆类型

  • 37
  • 4
单克隆

标记

  • 24
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GPR56 antibody is conjugated to PE

应用范围

  • 33
  • 17
  • 15
  • 4
  • 4
  • 3
  • 1
Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)

克隆位点

CG4
  • 纯化方法

    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    GPR56 (G Protein-Coupled Receptor 56 (GPR56))

    别名

    GPR56

    背景

    GPR56, also known as TM7XN1, is an orphan G-protein-coupled receptor (GPCR) containing seven transmembrane domains and a mucin-like domain in the N-terminal region. The total length of the human GPR56 gene is approximately 15 kb, and it consists of 13 exons and encodes 693 amino acids. GPR56 is expressed in a wide range of tissues, such as brain, thyroid gland, and heart. Mutations in human GPR56 gene were found to cause a specific brain malformation called bilateral frontoparietal polymicrogyria. Recently, GPR56 was found specifically expressed on cytotoxic NK and T lymphocytes, including CD8+, CD4+, and γδ T cells, which might affect the migratory properties of these cells. GPR56 was also found significantly downregulated in some cancer cells, suggesting that it may play a role in growth suppression and cancer metastasis.
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