GATA3 抗体 (PE)
Quick Overview for GATA3 抗体 (PE) (ABIN2662731)
抗原
See all GATA3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
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亚型
- IgG2b kappa
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anti-GATA Binding Protein 3 (GATA3) antibody
GATA3 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1A10A11 unconjugated
anti-GATA Binding Protein 3 (GATA3) (N-Term) antibodyGATA3 适用: 人, 小鼠, 大鼠, Cow, Pig, 犬, 斑马鱼, 兔, 豚鼠, 马, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 3 (GATA3) (AA 1-260) antibodyGATA3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 3 (GATA3) (AA 103-200) antibodyGATA3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C1 unconjugated
anti-GATA Binding Protein 3 (GATA3) (AA 103-200) antibodyGATA3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A4 unconjugated
anti-GATA Binding Protein 3 (GATA3) (pSer308) antibodyGATA3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 3 (GATA3) (C-Term) antibodyGATA3 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, 绵羊 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 3 (GATA3) (AA 1-444) antibodyGATA3 适用: 人 WB, FACS, IF 宿主: 小鼠 Monoclonal 1259CT707-136-102 unconjugated
anti-GATA Binding Protein 3 (GATA3) (AA 357-436) antibodyGATA3 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal GATA3-2442 unconjugated
anti-GATA Binding Protein 3 (GATA3) antibodyGATA3 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from prolonged exposure to light. Do not freeze.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- GATA3 (GATA Binding Protein 3 (GATA3))
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别名
- GATA3
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背景
- GATA3 functions as a major regulator of T helper 2 (Th2) cell differentiation in immune cells. GATA3 expression is upregulated through IL-4 receptor signaling or the Notch-mediated pathway, which results in production of IL-4, IL-5, and IL-13 cytokines, responsible for preferential differentiation of Th2-cells. GATA3 has been shown to regulate early developmental processes of T cells, such as T cell commitment, positive selection, and post-commitment CD4+ T cell survival. In the mammary gland, GATA3 plays an important role in differentiation and commitment of luminal epithelial cells. In a mouse model, exogenous expression of GATA3 in undifferentiated breast carcinoma cells induces differentiation and suppresses spreading of the tumor cells, suggesting that GATA3 is involved in preventing malignancy of breast cancer. GATA3 has been reported to be essential in the development of a variety of normal tissues. Defect in GATA3 results in hypoparathyroidism, sensorineural deafness, and renal dysplasia (HDR syndrome).
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途径
- Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
抗原
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