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CXCL5 抗体 (PE)

CXCL5 适用: 人 FACS 宿主: 小鼠 Monoclonal J111B7 PE
产品编号 ABIN2662704
发货至: 中国
  • 抗原 See all CXCL5 抗体
    CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CXCL5 antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    J111B7
    亚型
    IgG2b kappa
    Top Product
    Discover our top product CXCL5 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))
    别名
    CXCL5 (CXCL5 产品)
    别名
    ENA-78 antibody, SCYB5 antibody, Cxcl6 antibody, CXCL5 antibody, GCP-2 antibody, GCP2 antibody, SCYB6 antibody, AMCF-II antibody, LIX antibody, Scyb5 antibody, Scyb6 antibody, C-X-C motif chemokine ligand 5 antibody, C-X-C motif chemokine ligand 6 antibody, chemokine (C-X-C motif) ligand 5 antibody, C-X-C motif chemokine 5 antibody, CXCL5 antibody, Cxcl6 antibody, LOC701946 antibody, LOC703222 antibody, Cxcl5 antibody
    背景
    CXCL5, also known as ENA-78, is a 11.9 kD chemokine and belongs to the intercrine alpha, CXC chemokine family. It is expressed by monocytes and eosinophils in response to IL-1 and TNFα. CXCL5 can interact with CXCR2 and activate neutrophils and induce their migration. In vitro neutrophil chemotactic activity of CXCL5 is three fold higher. IFNγ suppresses expression of CXCL5. NFκB alone is sufficient to induce CXCL5 in contrast to IL-8, which requires both NFκB and C/EBP. Two forms are produced by N terminal proteolytic cleavage, ENA78 (8-78) and ENA 78 (9-78), and these isoforms exhibit higher chemotactic activity. Increased intra-hepatic levels of CXCL5 have been reported in patients with chronic liver disease.
    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity
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