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CD207 抗体 (PE)

CD207 适用: 人 IHC, FACS 宿主: 小鼠 Monoclonal 10E2 PE
产品编号 ABIN2662533
发货至: 中国
  • 抗原 See all CD207 抗体
    CD207 (CD207 Molecule, Langerin (CD207))
    适用
    • 40
    • 31
    • 20
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 40
    • 10
    小鼠
    克隆类型
    • 40
    • 10
    单克隆
    标记
    • 27
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This CD207 antibody is conjugated to PE
    应用范围
    • 41
    • 19
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Flow Cytometry (FACS)
    交叉反应
    Cynomolgus
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    10E2
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD207 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD207 (CD207 Molecule, Langerin (CD207))
    别名
    CD207 (CD207 产品)
    别名
    CD207 antibody, CLEC4K antibody, RGD1565913 antibody, CD207 molecule antibody, CD207 antigen antibody, CD207 antibody, Cd207 antibody
    背景
    CD207, also known as Langerin, is a 40 kD type II transmemberane cell glycoprotein which belongs to C-type lectin with mannose binding specificity. It is predominantly expressed on Langerhans cells and induces the formation of Birbeck granules, the Langerhans cell hallmark organelle. It is also found on several other subtypes of dendritic cells, such as dermal CD103-positive dendritic cells and splenic CD8-positive dendritic cells. Langerin is generally thought to be involved in antigen processing. Recently, it has been found that HIV captured by Langerin was internalized into Birbeck granule and degraded, which results in inhibition of HIV-1 infection and subsequent transmission.
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