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BCL6 抗体 (PE)

BCL6 适用: 人, 小鼠 FACS 宿主: 小鼠 Monoclonal IG191E-A8 PE
产品编号 ABIN2662400
发货至: 中国
  • 抗原 See all BCL6 抗体
    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
    适用
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    人, 小鼠
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This BCL6 antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    IG191E-A8
    亚型
    IgG1
    Top Product
    Discover our top product BCL6 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
    别名
    Bcl-6 (BCL6 产品)
    背景
    B-cell lymphoma 6 (Bcl-6), is an 80 kD homodimer and member of the BTB-POZ zinc finger family. It consists of one BTB (POZ) domain and six C2H2-type zinc fingers. Bcl-6 is a transcriptional repressor as well as a master regulator of germinal center reaction. On B cells, Bcl-6 induces proliferation, antibody class switching and affinity maturation, while inhibits its differentiation to plasma cells. On T cells, Bcl-6 induces its differentiation to TFH. This molecule is also expressed in some B cell lymphomas and breast cancer cells.
    途径
    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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