BATF 抗体 (PE)
Quick Overview for BATF 抗体 (PE) (ABIN2662396)
抗原
See all BATF 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
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亚型
- IgG2b kappa
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anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (AA 34-125) antibody
BATF 适用: 人 ELISA, WB, IP 宿主: 小鼠 Monoclonal 8A12 unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (AA 34-125) antibodyBATF 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1G4 unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (AA 1-126) antibodyBATF 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7C8F3 unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (AA 1-125) antibodyBATF 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) antibodyBATF 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (AA 34-125) antibodyBATF 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (AA 1-125) antibodyBATF 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (N-Term) antibodyBATF 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (AA 35-84) antibodyBATF 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, 猴, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from prolonged exposure to light. Do not freeze.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- BATF (Basic Leucine Zipper ATF-like Transcription Factor (BATF))
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别名
- BATF
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背景
- BATF is a basic leucine zipper transcription factor belonging to the ATF superfamily. BATF forms heterodimers with Jun proteins, which in turn binds to AP-1 consensus sites. The BATF/Jun heterodimers have significantly reduced transcriptional activity compared to Fos/Jun heterodimers. Therefore, induction of BATF expression suppresses AP-1 target genes by competing for Fos/Jun binding sequences. BATF is expressed at low levels in hematopoietic cells and can be induced in response to a variety of stimuli. BATF knockout mice show defects in cytokine expression and in the differentiation of T helper cell subsets and B cells, but not in the proliferation of lymphocytes. These findings suggest that BATF is a tissue-specific regulator for AP-1 activity and plays an essential role in the regulation of immune responses. During early EBV infection, BATF expression is induced by EBNA2 proteins, subsequently preventing infected B cells from entering apoptotic and lytic pathways. This indicates that BATF functions as a modulator to maintain latency status of virus-infected cells.
抗原
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