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Allergin-1 抗体 (PE)

MILR1 适用: 小鼠 ELISA (Capture) 宿主: 小鼠 Monoclonal TX83 PE
产品编号 ABIN2662383
发货至: 中国
  • 抗原 See all Allergin-1 (MILR1) 抗体
    Allergin-1 (MILR1) (Mast Cell Immunoglobulin-Like Receptor 1 (MILR1))
    适用
    • 26
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    小鼠
    宿主
    • 23
    • 2
    • 1
    小鼠
    克隆类型
    • 24
    • 2
    单克隆
    标记
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    • 1
    • 1
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    This Allergin-1 antibody is conjugated to PE
    应用范围
    • 13
    • 13
    • 9
    • 5
    • 3
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    ELISA (Capture)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    TX83
    亚型
    IgG1 kappa
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  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    Allergin-1 (MILR1) (Mast Cell Immunoglobulin-Like Receptor 1 (MILR1))
    别名
    Allergin-1 (MILR1 产品)
    别名
    Allergin-1 antibody, Gm885 antibody, Mca32 antibody, C17orf60 antibody, MCA-32 antibody, MCA32 antibody, mast cell immunoglobulin like receptor 1 antibody, mast cell immunoglobulin-like receptor 1 antibody, Milr1 antibody, MILR1 antibody
    背景
    Allergin-1, also known as mast cell Ag-32, is a 60 kD single pass transmembrane protein. It contains one Ig-like C2-type (immunoglobulin-like) domain in the extracellular region and one immunoreceptor tyrosine-based inhibitory motif (ITIM)-like domain in the cytoplasmic region. Allergin-1 is expressed on mast cells, dendritic cells, and macrophages as well as at low levels on neutrophils. After tyrosine phosphorylation, allergin-1 recruits PTPN6, PTPN11, and INPP5D, which results in a diminution of IgE-mediated degranulation in mast cells. No ligands have been identified for this molecule.
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