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CD53 抗体 (FITC)

This anti-CD53 antibody is a 大鼠 单克隆 antibody detecting CD53 in FACS. Suitable for 小鼠.
产品编号 ABIN2661775
发货至: 中国

Quick Overview for CD53 抗体 (FITC) (ABIN2661775)

抗原

See all CD53 抗体
CD53

适用

  • 67
  • 5
  • 4
小鼠

宿主

  • 40
  • 29
大鼠

克隆类型

  • 42
  • 24
  • 3
单克隆

标记

  • 33
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD53 antibody is conjugated to FITC

应用范围

  • 44
  • 33
  • 25
  • 18
  • 13
  • 13
  • 12
  • 12
  • 9
  • 9
  • 5
  • 4
  • 2
  • 1
Flow Cytometry (FACS)

克隆位点

OX-79
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.

    亚型

    IgM kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CD53

    别名

    CD53

    背景

    CD53 is a pan-leukocyte surface glycoprotein which spans the plasma membrane four times and is a member of the transmembrane 4 superfamily (TM4SF). CD53 is highly conserved in evolution, mouse CD53 was 91 % identical to rat and 82 % identical to human CD53. Mouse CD53 has a molecular mass of 35-45 kD and expresses on virtually all peripheral leukocytes, immature CD4-CD8- double negative thymocytes, and functionally mature CD4+CD8- or CD4-CD8+ single positive subsets. CD53 is proposed to play an important role in thymopoiesis and leukocyte signal transduction. It was reported that CD53 interact with a number of proteins, including CD2, CD9, CD19, and CD21. Cross-linking of CD53 promotes B cell activation. It was found that there is a strong correlation between CD53 expression and positive selection of thymocytes.
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