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CD45RB 抗体 (FITC)

CD45RB 适用: 小鼠 FACS, IHC, WB, IP 宿主: 大鼠 Monoclonal C363-16A FITC
产品编号 ABIN2661742
发货至: 中国
  • 抗原 See all CD45RB 抗体
    CD45RB
    适用
    • 57
    • 18
    • 10
    • 6
    • 5
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    • 2
    小鼠
    宿主
    • 47
    • 18
    • 12
    大鼠
    克隆类型
    • 76
    • 1
    单克隆
    标记
    • 23
    • 8
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
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    This CD45RB antibody is conjugated to FITC
    应用范围
    • 74
    • 41
    • 35
    • 26
    • 21
    • 17
    • 7
    • 4
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
    克隆位点
    C363-16A
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CD45RB Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD45RB
    别名
    CD45RB (CD45RB 产品)
    背景
    CD45RB is an isoform of CD45 with exon 5 splicing (encodes B determinant). It is a 220 kD glycoprotein expressed on peripheral B cells, naive T cells, thymocytes, weakly on macrophages, and dendritic cells. It plays a critical role in TCR and BCR signaling. As T cells become activated and progress from naive to memory cells, CD45RB expression is downregulated. Additionally, functionally distinct CD4+ T cell subsets, which secrete differing cytokine profiles, can be separated by CD45RB intensity. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4 and Thy-1.
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