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2B4 抗体 (FITC)

CD244 适用: 人 FACS 宿主: 小鼠 Monoclonal C1-7 FITC
产品编号 ABIN2661609
发货至: 中国
  • 抗原 See all 2B4 (CD244) 抗体
    2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This 2B4 antibody is conjugated to FITC
    应用范围
    • 56
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
    克隆位点
    C1-7
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD244 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
    别名
    CD244 (CD244 产品)
    别名
    CD244 antibody, 2B4 antibody, NAIL antibody, NKR2B4 antibody, Nmrk antibody, SLAMF4 antibody, C9.1 antibody, F730046O15Rik antibody, Ly90 antibody, CD244 molecule antibody, CD244 natural killer cell receptor 2B4 antibody, CD244 antibody, Cd244 antibody
    背景
    CD244, known as 2B4, is a 38 kD type I transmembrane protein. It is a member of the CD2 subset of the immunoglobulin superfamily (IgSF) molecules. CD244 is expressed on NK cells, a subset of T cells (including majority of CD8+ T cells and γ/δ T cells), monocytes, basophils, and eosinophils. CD48 is the ligand of CD244. It has been reported that ligation of human CD244 results in enhanced NK cell cytotoxicity and cytokine production. Recent studies have shown that human CD244, like murine CD244, has both activating and inhibitory functions, which are dependent on the density of surface 2B4 expression, degree of ligation, and the level of the adaptor molecule SAP expression.
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