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SIRPA 抗体 (FITC)

This anti-SIRPA antibody is a 大鼠 单克隆 antibody detecting SIRPA in ELISA, IHC, ICFC 和 CyTOF. Suitable for 小鼠.
产品编号 ABIN2661533
发货至: 中国

Quick Overview for SIRPA 抗体 (FITC) (ABIN2661533)

抗原

See all SIRPA 抗体
SIRPA (Signal-Regulatory Protein alpha (SIRPA))

适用

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小鼠

宿主

  • 68
  • 39
  • 1
  • 1
  • 1
大鼠

克隆类型

  • 61
  • 48
  • 1
单克隆

标记

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  • 2
  • 2
  • 2
  • 1
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This SIRPA antibody is conjugated to FITC

应用范围

  • 69
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  • 3
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ELISA, Immunohistochemistry (IHC), Intracellular Flow Cytometry (ICFC), Mass Cytometry (CyTOF)

克隆位点

P84
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    SIRPA (Signal-Regulatory Protein alpha (SIRPA))

    别名

    CD172a

    背景

    CD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces the recruitment and activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D.
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