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CD16 抗体 (FITC)

This anti-CD16 antibody is a 小鼠 单克隆 antibody detecting CD16 in FACS 和 ICFC. Suitable for 人.
产品编号 ABIN2661358
发货至: 中国

Quick Overview for CD16 抗体 (FITC) (ABIN2661358)

抗原

See all CD16 抗体
CD16

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD16 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

克隆位点

B73-1
  • 纯化方法

    The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC and unconjugated antibody.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CD16

    别名

    CD16

    背景

    CD16 is known as low affinity IgG receptor III (FcγRIII). It is expressed as two distinct forms (CD16a and CD16b). CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, a subset of T cells and placental trophoblasts in humans. CD16b (FcγRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95 % homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC).

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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