NTAN1 抗体 (Biotin)
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- 抗原 See all NTAN1 抗体
- NTAN1 (N-terminal Asparagine Amidase (NTAN1))
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适用
- 人, 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This NTAN1 antibody is conjugated to Biotin
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- The solution is free of unconjugated biotin.
- 克隆位点
- MECA-79
- 亚型
- IgM kappa
- Top Product
- Discover our top product NTAN1 Primary Antibody
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anti-N-terminal Asparagine Amidase (NTAN1) (AA 219-310) antibody
NTAN1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-N-terminal Asparagine Amidase (NTAN1) antibodyNTAN1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-N-terminal Asparagine Amidase (NTAN1) (AA 1-310) antibodyNTAN1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-N-terminal Asparagine Amidase (NTAN1) (AA 1-310) antibodyNTAN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- NTAN1 (N-terminal Asparagine Amidase (NTAN1))
- 别名
- PNAd (NTAN1 产品)
- 别名
- PNAA antibody, PNAD antibody, N-terminal Asn amidase antibody, N-terminal asparagine amidase antibody, Ntan1 antibody, NTAN1 antibody
- 背景
- MECA-79 recognizes a carbohydrate epitope shared with a group of sulfation decorated sialomucins, including sulfated ligands for CD62L (CD34, GlyCAM-1, Sgp200, and a subset of MAdCAM-1). This set antigens has been referred to as peripheral node addressin (PNAd) with the molecular mass 50-250 kD. It has been identified that GlcNAc-6-SO4 sulfation contributes to MECA-79 binding and the core 1 β1,3-N-acetylglucosaminyltransferase is required for the generation of the MECA-79 epitope. MECA-79 is expressed on high endothelial venules (HEV) of lymphoid tissues, chronic inflamed tissues and rheumatoid synovia. The interaction of PNAd with CD62L receptor is involved in tethering and rolling of lymphocytes along HEV in lymphoid tissues. MECA-79 antibody reacts with mouse, human and many other species PNAd and blocks L-selectin-dependent lymphocyte adhesion in vitro and in vivo.
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