IL-33 抗体 (Ser109) (Biotin)
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- 抗原 See all IL-33 (IL33) 抗体
- IL-33 (IL33) (Interleukin 33 (IL33))
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抗原表位
- Ser109
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适用
- 小鼠, 大鼠
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This IL-33 antibody is conjugated to Biotin
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应用范围
- Flow Cytometry (FACS)
- 交叉反应
- 大鼠
- 纯化方法
- The antibody was purified by antigen affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
- 免疫原
- Ser109-Isoleucin266 (Accession# NM_133775) was expressed in E. coli.
- 克隆位点
- Poly5165
- 亚型
- Ig Fraction, IgG
- Top Product
- Discover our top product IL33 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.2 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 1 % BSA and 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- IL-33 (IL33) (Interleukin 33 (IL33))
- 别名
- IL-33 (IL33 产品)
- 别名
- IL33 antibody, C9orf26 antibody, DVS27 antibody, IL1F11 antibody, NF-HEV antibody, NFEHEV antibody, RP11-575C20.2 antibody, 9230117N10Rik antibody, Il-33 antibody, Il1f11 antibody, RGD1311155 antibody, interleukin 33 antibody, IL33 antibody, Il33 antibody
- 背景
- IL-33 belongs to the IL-1 family and is closely related in structure to IL-18 and IL-1b. IL-33, IL-1b, and IL-18 are synthesized as biologically inactive precursor and are cleaved by the enzyme caspase-1 to be secreted as active mature forms. IL-33 stimulates target cells by binding to the IL-1R/TLR superfamily member ST2 and subsequently activates NF-κB and MAPK pathways via identical signalling events to those observed for IL-1b. In addition, IL-33 is a nuclear factor (NF-HEV) abundantly expressed in high endothelial venules from lymphoid organs that associates with chromatin and exhibits transcriptional regulatory properties.
- 途径
- Production of Molecular Mediator of Immune Response
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