IL-33 抗体 (Ser109) (Biotin)
Quick Overview for IL-33 抗体 (Ser109) (Biotin) (ABIN2661329)
抗原
See all IL-33 (IL33) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Ser109
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交叉反应
- 大鼠
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纯化方法
- The antibody was purified by antigen affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
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免疫原
- Ser109-Isoleucin266 (Accession# NM_133775) was expressed in E. coli.
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亚型
- Ig Fraction, IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 1 % BSA and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- IL-33 (IL33) (Interleukin 33 (IL33))
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别名
- IL-33
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背景
- IL-33 belongs to the IL-1 family and is closely related in structure to IL-18 and IL-1b. IL-33, IL-1b, and IL-18 are synthesized as biologically inactive precursor and are cleaved by the enzyme caspase-1 to be secreted as active mature forms. IL-33 stimulates target cells by binding to the IL-1R/TLR superfamily member ST2 and subsequently activates NF-κB and MAPK pathways via identical signalling events to those observed for IL-1b. In addition, IL-33 is a nuclear factor (NF-HEV) abundantly expressed in high endothelial venules from lymphoid organs that associates with chromatin and exhibits transcriptional regulatory properties.
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途径
- Production of Molecular Mediator of Immune Response
抗原
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