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- 抗原 See all CRLF2 抗体
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CRLF2 antibody is conjugated to Biotin
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应用范围
- Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 纯化方法
- The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
- 克隆位点
- 1B4
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CRLF2 Primary Antibody
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anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 81-180) antibody
CRLF2 适用: 人 ELISA, IF (p), IF (cc), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-231) antibodyCRLF2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-132) antibodyCRLF2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A11 unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 71-120) antibodyCRLF2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (AA 23-231) antibodyCRLF2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) antibody (Carboxyfluorescein (CFS))CRLF2 适用: 小鼠 FACS 宿主: 山羊 Polyclonal Carboxyfluorescein (CFS)
anti-Cytokine Receptor-Like Factor 2 (CRLF2) (Center) antibodyCRLF2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Cytokine Receptor-Like Factor 2 (CRLF2) antibodyCRLF2 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 8H8 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
- 别名
- TSLPR (CRLF2 产品)
- 别名
- CRLF2 antibody, CRL2 antibody, CRLF2Y antibody, TSLPR antibody, CRLM2 antibody, Ly114 antibody, Tpte2 antibody, Tslpr antibody, Crl2 antibody, cytokine receptor like factor 2 antibody, cytokine receptor-like factor 2 antibody, CRLF2 antibody, Crlf2 antibody
- 背景
- TSLP-R, also known as the thymic stromal lymphopoietin protein receptor, cytokine receptor-like 2, CRL2, and IL-XR, is a type I membrane receptor that forms a functional heterodimeric complex with IL-7R to bind with TSLP. The TSLP-R contains a WSXWS motif required for proper protein folding and a box1 motif important for association with the JAKs. TSLP-R has a predicted molecular weight approximately 40 kD, and has two isoforms reported that are produced by alternative splicing. The TSLP-R is expressed preferentially in myeloid cells, dendritic cells, and activated monocytes. It is weakly expressed in T cells. Expression has also been reported in heart, skeletal, muscle, and kidney tissues. TSLP binding to the heterodimeric functional receptor (TSLP-R and IL-7R) activates JAK2, STAT3, and STAT5 to stimulate cell proliferation. Ligand receptor interactions have been implicated in the development of the hematopoietic system, dendritic cell maturation, and the maintenance and polarization of human Th2 memory T cells in allergy diseases.
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