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IL17F 抗体 (Biotin)

IL17F 适用: 小鼠 IHC, FACS, IF, CyTOF 宿主: 小鼠 Monoclonal 8F5-1A9 Biotin
产品编号 ABIN2661211
发货至: 中国
  • 抗原 See all IL17F 抗体
    IL17F (Interleukin 17F (IL17F))
    适用
    • 77
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    小鼠
    宿主
    • 79
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    小鼠
    克隆类型
    • 84
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    单克隆
    标记
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    This IL17F antibody is conjugated to Biotin
    应用范围
    • 69
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    Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Cytometry by Time of Flight (CyTOF)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
    克隆位点
    8F5-1A9
    亚型
    IgG1 kappa
    Top Product
    Discover our top product IL17F Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    IL17F (Interleukin 17F (IL17F))
    别名
    IL-17F (IL17F 产品)
    别名
    CANDF6 antibody, IL-17F antibody, ML-1 antibody, ML1 antibody, C87042 antibody, IL17F antibody, interleukin 17F antibody, IL17F antibody, Il17f antibody
    背景
    Interleukin 17F (IL-17F) is a 37 kD IL-17 family member. The IL-17 family consists of six members including IL-17 (also called IL-17A), IL-17B, IL-17C, IL-17D, IL-17E (also called IL-25), and IL-17F. IL-17F shares the strongest similarity to IL-17A and forms a homodimer or heterodimer with IL-17A. It is produced by Th17 cells, mast cells, basophils, and epithelial cells. IL-17F is an important regulator of inflammatory responses. It is involved in host defense against mucoepithelial infection by Staphylococcus aureus and Citrobacter rodentium. Overexpression of the IL-17F gene in the airways of mice is associated with airway neutrophilia, the induction of many cytokines, an increase in airway hyperreactivity, and mucus hypersecretion. IL-17F is also involved in cancer immunity and autoimmune responses. IL-17F, like IL-17A, depends on IL-17R for its signaling in vitro and in vivo. P38 MAPK, ERK1/2, Act1 (NF-kB activator protein 1), and TRAF6 are involved in IL-17F signaling.
    途径
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
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