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IL17F 抗体 (Biotin)

This anti-IL17F antibody is a 小鼠 单克隆 antibody detecting IL17F in IHC, FACS, IF 和 CyTOF. Suitable for 小鼠.
产品编号 ABIN2661211
发货至: 中国

Quick Overview for IL17F 抗体 (Biotin) (ABIN2661211)

抗原

See all IL17F 抗体
IL17F (Interleukin 17F (IL17F))

适用

  • 80
  • 30
  • 20
小鼠

宿主

  • 82
  • 24
  • 2
小鼠

克隆类型

  • 85
  • 22
  • 1
单克隆

标记

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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This IL17F antibody is conjugated to Biotin

应用范围

  • 75
  • 52
  • 27
  • 21
  • 14
  • 9
  • 7
  • 4
  • 4
  • 3
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Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Cytometry by Time of Flight (CyTOF)

克隆位点

8F5-1A9
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    IL17F (Interleukin 17F (IL17F))

    别名

    IL-17F

    背景

    Interleukin 17F (IL-17F) is a 37 kD IL-17 family member. The IL-17 family consists of six members including IL-17 (also called IL-17A), IL-17B, IL-17C, IL-17D, IL-17E (also called IL-25), and IL-17F. IL-17F shares the strongest similarity to IL-17A and forms a homodimer or heterodimer with IL-17A. It is produced by Th17 cells, mast cells, basophils, and epithelial cells. IL-17F is an important regulator of inflammatory responses. It is involved in host defense against mucoepithelial infection by Staphylococcus aureus and Citrobacter rodentium. Overexpression of the IL-17F gene in the airways of mice is associated with airway neutrophilia, the induction of many cytokines, an increase in airway hyperreactivity, and mucus hypersecretion. IL-17F is also involved in cancer immunity and autoimmune responses. IL-17F, like IL-17A, depends on IL-17R for its signaling in vitro and in vivo. P38 MAPK, ERK1/2, Act1 (NF-kB activator protein 1), and TRAF6 are involved in IL-17F signaling.

    途径

    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
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