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CD8 alpha 抗体 (Biotin)

This anti-CD8 alpha antibody is a 小鼠 单克隆 antibody detecting CD8 alpha in FACS 和 WB. Suitable for 人.
产品编号 ABIN2661148
发货至: 中国

Quick Overview for CD8 alpha 抗体 (Biotin) (ABIN2661148)

抗原

See all CD8 alpha (CD8A) 抗体
CD8 alpha (CD8A) (CD8a Molecule (CD8A))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD8 alpha antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS), Western Blotting (WB)

克隆位点

RPA-T8
  • 交叉反应

    Chimpanzee, Baboon, Cynomolgus, 猕猴, Pigtailed Macaque, Sooty mangabey (Cercocebus atys)

    纯化方法

    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CD8 alpha (CD8A) (CD8a Molecule (CD8A))

    别名

    CD8a

    背景

    CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation, and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

    途径

    TCR Signaling
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