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CD8 alpha 抗体 (Biotin)

This anti-CD8 alpha antibody is a 小鼠 单克隆 antibody detecting CD8 alpha in FACS. Suitable for 人.
产品编号 ABIN2661146
发货至: 中国

Quick Overview for CD8 alpha 抗体 (Biotin) (ABIN2661146)

抗原

See all CD8 alpha (CD8A) 抗体
CD8 alpha (CD8A) (CD8a Molecule (CD8A))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD8 alpha antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS)

克隆位点

HIT8a
  • 交叉反应

    Chimpanzee, Marmoset

    纯化方法

    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CD8 alpha (CD8A) (CD8a Molecule (CD8A))

    别名

    CD8a

    背景

    CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

    途径

    TCR Signaling
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