CD51/CD61 抗体 (Biotin)
Quick Overview for CD51/CD61 抗体 (Biotin) (ABIN2661110)
抗原
See all CD51/CD61 (ITGAV/ITGB3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 兔, 小鸡
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纯化方法
- The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
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亚型
- IgG1 kappa
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anti-Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3) antibody
ITGAV/ITGB3 适用: 人, 小鼠, 大鼠 FACS, WB, IHC (fro), IF (cc), IF (p), ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3) antibodyITGAV/ITGB3 适用: 人, 小鸡, 兔 FACS, IHC (fro), IHC 宿主: 小鼠 Monoclonal 23C6 unconjugated
anti-Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3) antibody (FITC)ITGAV/ITGB3 适用: 人 FACS 宿主: 小鼠 Monoclonal 23C6 FITC
anti-Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3) antibodyITGAV/ITGB3 适用: 人, 小鸡 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal 23C6 unconjugated
anti-Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3) antibody (PE)ITGAV/ITGB3 适用: 人, 小鸡 FACS 宿主: 小鼠 Monoclonal 23C6 PE
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))
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别名
- CD51/61
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背景
- CD51/CD61 is an integrin complex known as αVβ3. It is expressed at high levels on osteoclasts, endothelial cells, and melanoma cells and at low levels on platelets and macrophages. CD51 is a heterodimer composed of disulfide-linked 125 kD and 24 kD proteins. CD61 is also a member of the integrin family known as gpIIIa or β3 integrin. It is a 110 kD common β subunit of CD51/CD61 or CD41/CD61 complex. CD51/CD61, also known as the vitronectin receptor, mediates the binding of platelets to immobilized vitronectin without prior activation. Other ligands include RGD-containing proteins such as fibrinogen, fibronectin, von Willebrand factor (vWf), laminin, thrombospondin and the neural adhesion molecule L1. CD51/CD61 also mediates cell-cell adhesion via interaction with CD31. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins, including matrix components. The 23C6 antibody has been reported to be useful for blocking studies.
抗原
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