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ITGA4 抗体 (Biotin)

This anti-ITGA4 antibody is a 大鼠 单克隆 antibody detecting ITGA4 in FACS, WB, IHC 和 IP. Suitable for 小鼠.
产品编号 ABIN2661099
发货至: 中国

Quick Overview for ITGA4 抗体 (Biotin) (ABIN2661099)

抗原

See all ITGA4 抗体
ITGA4 (Integrin alpha 4 (ITGA4))

适用

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小鼠

宿主

  • 76
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  • 27
大鼠

克隆类型

  • 100
  • 62
  • 2
单克隆

标记

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This ITGA4 antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

克隆位点

9C10 (MFR4-B)
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    ITGA4 (Integrin alpha 4 (ITGA4))

    别名

    CD49d

    背景

    CD49d is a 150 kD glycoprotein, also known as α4 integrin or VLA-4 α chain. It is a member of the integrin family, expressed on T and B cells, monocytes, eosinophils, basophils, mast cells, thymocytes, NK cells, and dendritic cells. CD49d is a heterodimer expressed with either of two β chains, β1 (CD29) or β7, to form the VLA-4 (integrin α4β1) or LPAM-1 (integrin α4β7) complexes. CD49d plays a critical role in both adhesion and T cell costimulation. The primary ligands for CD49d are VCAM-1, MAdCAM-1, and fibronectin. The 9C10(MFR4.B) antibody, in combination with the R1-2 monoclonal antibody, completely blocks VCAM-1 binding to VLA-4.

    途径

    Integrin Complex
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